The following is a list of major grants awarded to the Cabrini Monash University Department of Surgery for bowel cancer research and medical treatment projects.

Grants awarded:

2022

Margaret Walkom Trust

Improving outcomes for bowel cancer patients through the patient-reported outcome measures program.

CI Dr Christine Georges

Funding provided                                                                                                                               $90,000

 

2021

The CASS Foundation

Using patient-derived tumouroids to guide “watch and wait” approach in rectal cancer

CI Dr Rebekah Engel

Funding provided                                                                                                                               $57,000

 

Cabrini Foundation Research Grant                                                                                              

Personalising cancer medicine part II: Expanding the organoid program to include treatment-exposed metastatic colorectal cancer.’

CIs R Engel, S Mendis, P McMurrick, H Abud

Funding provided                                                                                                                               $30,000

 

Cabrini Foundation Research Grant

Regulation of the immune response in the colorectal cancer tumour microenvironment and its role in patient outcomes

CIs Wilkins S, Fletcher A, Georges C, McMurrick P.

Funding provided                                                                                                                               $30,000

 

2020

Cabrini Foundation Research Grant                                                                                             

Personalising cancer medicine: the development of a high throughput drug screening platform using patient-derived colorectal cancer organoids
Dr Rebekah Engel, Prof Paul McMurrick

Funding provided                                                                                                                               $30,000

 

2019

Eirene Lucas Foundation                                                                                                                

Anti-cancer compound library resource for drug discovery
Dr Rebekah Engel, Prof Paul McMurrick

Funding provided                                                                                                                               $10,000

 

Alan, Ada and Eva Selwyn Clinical Research Grant                                                                    

Personalised medicine for colorectal cancer patients: Utilisation of Organoid Technology, Tissue micro-arrays and consensus molecular subtypes

CIs Dr Christine Georges, Dr Rebekah Engel, Karen Oliva, Prof Paul McMurrick

Funding provided                                                                                                                              $30,000

 

Cabrini Foundation Research Grant                                                                               

Developing a new tissue-slice assay for modelling colorectal cancer tumours

Dr Simon Wilkins, Dr Anne Fletcher, Dr Kostas Knoblich, Prof Paul McMurrick

Funding provided                                                                                                                               $30,000

 

2018

Cabrini Clinical Research Grant                                                                                       

Using patient-derived organoids to guide the nonsurgical “watch and wait” approach for rectal cancer

CIs Dr Rebekah Engel, Prof Paul McMurrick

Funding provided                                                                                                                               $30,000

 

Cancer Australia Grant                                                                                                     

Translating colorectal cancer organoids into patient care

CIs Abud, Worthley, Burgess, McMurrick, Firestein, Gibbs, Clevers, Price, Padbury, Hewett

Funding provided                                                                                                                               $597,556

 

2017                                                                                                                       

Margaret Walkom Trust                                                                                                                  

Genetic testing of colorectal cancer       

CIs Dr Christine Georges, Dr Simon Wilkins, Prof Paul McMurrick

Funding provided                                                                                                                               $30,000

 

The Collie Foundation                                                                                                       

Colorectal cancer organoids project

CIs Prof Paul McMurrick, Prof Helen Abud, Dr Simon Wilkins, Dr Rebekah Engel, Ms Karen Oliva

Funding provided                                                                                                                               $300,000

 

Urquhart Charitable Fund                                                                                                               

Project funding to develop patient education with a view to expanding uptake of the National Bowel Cancer Screening Program (NBCSP).

CI Prof Paul McMurrick

Funding provided                                                                                                                               $14,490

 

2016

The Collie Foundation                                                                                                       

Patient Reported Outcome Measures (PROMs)

CIs Prof Paul McMurrick, Dr Simon Wilkins, Ms Karen Oliva

Funding provided                                                                                                                               $40,000

 

Margaret Walkom Trust                                                                                                                  

Project: Genetic testing of colorectal cancer       

CIs Prof Paul McMurrick, Dr Simon Wilkins

Funding provided                                                                                                                               $30,000

 

Victorian Cancer Agency (VCA) Translational Research Project                                              

Super-enhanced template RNAs as predictive biomarkers of BET inhibitor sensitivity in prostate and colorectal cancer.

Dr Arun Azad, Dr Ron Firestein, Prof Helen Abud, Prof Paul McMurrick, Prof Gail Risbridger, Dr Simon Wilkins

Funding provided                                                                                                                               $2 million

 

CSSANZ grant                                                                                                                      

ADIPOSe- Australasian Decrease in Intra-Pelvic Obesity for Surgery Trial- Using VLED’s to reduce weight and improve outcomes in obese individuals undertaking rectal cancer surgery

CIs Mr Stephen Bell, Prof Paul McMurrick and Dr Simon Wilkins

Funding provided                                                                                                                               $100,000

 

2015

Cabrini Foundation Grant                                                                                                               

ADIPOSe- Australasian Decrease in Intra-Pelvic Obesity for Surgery Trial- Using VLED’s to reduce weight and improve outcomes in obese individuals undertaking rectal cancer surgery

CIs Mr Stephen Bell, Prof Paul McMurrick, Dr Simon Wilkins

Funding provided                                                                                                                               $50,000             

NHMRC Project Grant Application APP1100531                                                          

“Defining the function of Snai1 in stem cells and colorectal cancer”. 
CIs H. Abud, G. Hime, L. Jones, P. McMurrick, V. Perreau

Funding provided                                                                                                                              $646,698

 

2011

NHMRC Project Grant Application APP1010429,                                                                         2011-2013

“Functional studies on the role of DNp73 in stem cells and cancer”. 
Cis H. Abud, G. Hime, T. Stiewe, P.J. McMurrick. 

Funding provided                                                                                                                              $414,208

 

NHMRC Development Grant Application APP1017078                                              

“Blood based diagnostic assay for diagnosis of colorectal cancer”. 
Chief Investigator (CIE) P McMurrick

Funding provided                                                                                                                              $542,260

 

2002

NHMRC Grant Application 207815,                                                                                               

“Australasian Multi Centered Prospective Randomised Study of Laparoscopic Versus Conventional Surgical Treatment of Colon Cancer”.

CIs P Hewett, N Rieger, A Stevenson, M Solomon, P McMurrick, P Bagshaw. 

Funding provided                                                                                                                              $495,000

 

1999

Cabrini Clinical Education and Research Foundation Research Grant                                   

Title of Project, ‘Determining the Incidence and Clinical Correlations of Micro Satellite Instability in Colorectal Cancers in Patients Under the Age of 50 Years’. 
CIs PJ McMurrick, H Debinski, A Polglase